18. Phoenix
Increase in Cost to Live Comfortably: $12,603.84
Percentage Increase to Cost to Live Comfortably: 23.69 percent
The cost of healthcare in Arizona is much higher than the rest of the country, with the average annual costs exceeding $6,000. That said, the fourth-lowest annual grocery costs mean that, although costs are rising rapidly, the $65,000 a year or so you’ll need to live comfortably in Phoenix isn’t excessive for a big city.